Clinical, Behavioral & Outcomes Research

Leading the way in understanding genetic and environmental determinants

How We're Advancing Care

The section on Clinical, Behavioral, and Outcomes Research aims to elucidate the underlying genetic and environmental determinants of type 1 and type 2 diabetes and its complications, and develop new treatments to prevent or delay the development of diabetes and its complications in high-risk individuals.

The section has an active clinical research environment to train future investigators. The scope of ongoing investigations ranges from small physiologic projects to NIH-funded multi-center trials. There are over 300 unique, active IRB-approved human protocols at the Joslin, of which about 175 involve active patient participation.

These studies include a wide range of investigations that can be described as observational (55 percent) or interventional (45 percent); single site (60 percent) or multicenter (40 percent); and involve participants who are adult (80 percent), pediatric (7.5 percent), or both (10 percent). Studies are led by more than 47 PIs (many of whom are in other Joslin sections). Investigators in the section collaborate extensively with members of basic research sections at the Joslin and with investigators in the surrounding Harvard-affiliated teaching hospitals and at other academic institutions.

Section Members

Jason Gaglia, MD, MMSc
Jason Gaglia, MD, MMSc Section Head, Clinical, Behavioral and Outcomes Research
Co-Director, Clinical Translational Research Core
Research Interest Immunobiology
Lori Laffel, MD, MPH
Lori Laffel, MD, MPH Chief, Pediatric, Adolescent, and Young Adult Section
Section Head, Clinical, Behavioral and Outcomes Research
Director, Clinical Translational Research Core
Florence Brown, MD
Florence Brown, MD Co-Director, Pregnancy Program Research Interest Clinical Behavioral and Outcomes
Om Ganda, MD
Om Ganda, MD Medical Director, Lipid Clinic Research Interest Clinical Behavioral and Outcomes
Osama Hamdy, MD, PhD
Osama Hamdy, MD, PhD Director, International Medical Affairs
Medical Director, Obesity Clinic Program and Inpatient Diabetes Program
Research Interest Clinical Behavioral and Outcomes
Elvira Isganaitis, MD, MPH
Elvira Isganaitis, MD, MPH Research Interest Integrative Physiology and Metabolism
Sanjeev Mehta, MD, MPH
Sanjeev Mehta, MD, MPH Chief Medical Officer
Chief Medical Information Officer
Research Interest Genetics and Epidemiology
Sylvia Rosas, MD, MSCE
Sylvia Rosas, MD, MSCE Director, Latino Kidney Clinic
Mark Williams, MD
Mark Williams, MD Director, Dialysis