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Insulin Action

There are several types of insulin. They are classified by how long they act and are generally referred to as  rapid-acting, short-acting, intermediate and long-acting. Each type of insulin has a certain time period in which it works.  In order to understand insulin action more completely, it is helpful to know the onset, peak, and duration of the insulin you take.

  • Onset refers to when the insulin starts to work.
  • Peak refers to when the insulin is working its hardest.
  • Duration refers to how long the insulin works.

The chart below describes the insulin action of the the types of insulin most commonly used in treating diabetes.

 

 

Types of insulin

  PRODUCT WHEN TO TAKE ONSET PEAK DURATION
Rapid-Acting

Lispro (Humalog)

Aspart (Novolog)

Glulisine (Apidra)

0-15 min before meal 10-30 min 30 min - 3 hours 3-5 hours
Short-Acting

Regular (R)

Human

30 min before meal 30-60 min 2-5 hours Up to 12 hours
Intermediate-Acting

NPH (N)

Human

Does not need to be given with meal 90 min - 4 hours 4-12 hours Up to 24 hours
Long Acting

Glargine (Lantus)

Detemir (Levemir)

Does not need to be given with meal 45 min - 4 hours Minimal Up to 24 hours

 

 

 

 

 

 

 

 

For more information, you may want to purchase our book What You Need to Know About Diabetes - A Short Guide, which can be ordered online.

 
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